No More Heroes 2: Desperate Struggle
| USA | Europe | Japan | Russia | |
| WiiWii | Jan 26, 2010 | May 28, 2010 | Oct 21, 2010 | – |
| Nintendo SwitchNSwitch | Oct 28, 2020 | Oct 28, 2020 | – | Oct 28, 2020 |
| PCPC | Jun 9, 2021 | Jun 9, 2021 | – | – |
Minimum:
- OS: Windows 8.1
- CPU: Intel Core i5-4460
- RAM (memory): 8 GB
- Videocard: NVIDIA GeForce GTX750Ti
- DirectX 11
- HDD: 4 GB free space
Recommended:
- OS: Windows 8.1
- CPU: Intel Core i5-4670
- RAM (memory): 8 GB
- Videocard: NVIDIA GeForce GTX 970
- DirectX 11
- HDD: 4 GB free space
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